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AQA A-Level Chemistry: Chromatography Techniques in Organic Chemistry — mark scheme explained

Machine-verifiedchecked against the AQA A-Level Chemistry specificationlast verified 2 July 2026

The short answer

Chromatography is a powerful analytical technique used to separate and identify components in a mixture. It plays a crucial role in organic chemistry, particularly for the purification and analysis of complex mixtures. This section covers three main types of chromatography: thin-layer chromatography (TLC), column chromatography (CC), and gas chromatography (GC).

The question

A TLC plate was developed using a solvent. The distance traveled by the solvent front (d s ) is 5 cm. A spot for an unknown compound is found at a distance of 2 cm from the origin. Calculate the R f value for this compound. [Paraphrased for study — not reproduced from any exam paper.]

Mark scheme, decoded

What each mark is really for — in plain English — and the wording trap that loses it.

  • S1

    Step 1: Identify the given values.

  • S2

    Distance traveled by the solvent front (d s ) = 5 cm

  • S3

    Distance traveled by the substance (d c ) = 2 cm

  • S4

    Step 2: Use the formula for R f value.

  • S5

    R f = d c / d s

  • S6

    Step 3: Substitute the values into the formula.

  • S7

    R f = 2 cm / 5 cm

  • S8

    Step 4: Perform the division.

  • S9

    R f = 0.4

Model answer

Worked through, with each step tagged to the mark it earns.

  1. S1

    Step 1: Identify the given values.

  2. S2

    Distance traveled by the solvent front (d s ) = 5 cm

  3. S3

    Distance traveled by the substance (d c ) = 2 cm

  4. S4

    Step 2: Use the formula for R f value.

  5. S5

    R f = d c / d s

  6. S6

    Step 3: Substitute the values into the formula.

  7. S7

    R f = 2 cm / 5 cm

  8. S8

    Step 4: Perform the division.

  9. S9

    R f = 0.4

  10. Final answer: 0.4

Common mistakes

  • Using the wrong distances to calculate R f values. — Always measure the distance from the origin to the center of the spot for accurate R f values.
  • Forgetting to use the correct formula for R f values. — Always use the formula R f = distance traveled by the substance / distance traveled by the solvent front.
  • Confusing retention times with R f values. — Remember that retention times are used in GC, while R f values are used in TLC. Retention times measure time, while R f values measure distance.
  • Misinterpreting chromatograms. — Practice analyzing chromatograms by identifying the solvent front, measuring distances accurately, and comparing with known standards. Ensure you understand the principles of separation in each technique.
  • Incorrectly calculating relative retention times (R r ). — Always use the correct formula for relative retention time and double-check your calculations to ensure accuracy.
  • Failing to explain the principles of separation clearly. — Practice explaining the principles step-by-step. Emphasize how substances are separated based on their interactions with the mobile and stationary phases in each technique (TLC, CC, GC).

Where the marks go

  • Full worked solution (all marking points)3 marks

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